What's New on PhysioNet?

WFDB Software Package
Over 70 open-source applications for signal processing, analysis, and more, all built on a stable and easy-to-use library that can be incorporated into your own software. Latest update: Friday, 29 May 2015 (summary here).
15 September 2016
The ECG effects of Dofetilide, Moxifloxacin, Dofetilide+Mexiletine, Dofetilide+Lidocaine and Moxifloxacin+Diltiazem in Healthy Subjects database contains data from a randomized, double-blind, 5-period crossover clinical trial in healthy male and female subjects, 18 to 35 years of age, to compare the electrophysiological response of hERG potassium channel blocking drugs with and without the addition of late sodium or calcium channel blocking drugs. The dataset and its collection methods are described in Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.
3 September 2016
The MAMEM steady state visually evoked potentials database has been updated with a third experimental dataset.
26 July 2016
The ECG Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects database contains multi-channel ECG recordings of subjects partaking in a randomized, double-blind, 5-period crossover clinical trial aimed at comparing the effects of four known QT prolonging drugs versus placebo on electrophysiological and other clinical parameters. The dataset and its collection methods are described in Differentiating Drug-Induced Multichannel Block on the Electrocardiogram: Randomized Study of Dofetilide, Quinidine, Ranolazine, and Verapamil.
20 June 2016
The Long Term Movement Monitoring database contains 3-day 3D accelerometer recordings of 71 elder community residents, used to study gait, stability, and fall risk. The dataset and its collection methods are described in Does the Evaluation of Gait Quality During Daily Life Provide Insight Into Fall Risk? : A Novel Approach Using 3-Day Accelerometer Recordings.
9 June 2016
The Indwelling Arterial Catheter Clinical dataset, contains clinical data for 1776 patients from the MIMIC-II clinical database. It was the basis for the article: Hsu DJ, et al. The association between indwelling arterial catheters and mortality in hemodynamically stable patients with respiratory failure: A propensity score analysis. Chest, 148(6):1470–1476, Aug. 2015. This dataset was also used by Raffa et al. in Chapter 5 "Data Analysis" of the forthcoming book: Secondary Analysis of Electronic Health Records, published by Springer in 2016.
8 June 2016
The MAMEM steady state visually evoked potentials database containing 256 channel EEG recordings of 11 subjects under the stimulation of flickering lights has been expanded with a second experimental dataset.
19 May 2016
The Human Balance Evaluation database contains force platform recordings from 193 subjects undergoing stabilography tests. This dataset is contributed by the BMC-Lab of the Federal University of ABC.
29 April 2016
The fetal ECG synthetic database is a large database of simulated adult and non-invasive fetal ECG (NI-FECG) signals, which provides a robust resource that enables reproducible research in the field. The data is generated using the FECGSYN simulator (visit website). The dataset and its collection methods are described in An Open-Source Framework for Stress-Testing Non-Invasive Foetal ECG Extraction Algorithms.
19 April 2016
The Association for the Advancement of Medical Instrumentation (AAMI) announced that the Foundation’s highest honor, the Laufman-Greatbatch Award for 2016, was being awarded for the creation and development of the PhysioNet Resource.
15 April 2016
The Squid Giant Axon Membrane Potential database contains single-unit neuronal recordings of squid giant axons in response to stimulus currents. The membrane potential and stimulus current are given for a total of 170 trials across 8 different axons. The dataset and its collection methods are described in Noisy Inputs and the Induction of On-Off Switching Behavior in a Neuronal Pacemaker.
15 April 2016
The MAMEM steady state visually evoked potentials database contains 256 channel EEG recordings of 11 subjects under the stimulation of flickering lights. The dataset and its collection methods are described in Comparative evaluation of state-of-the-art algorithms for SSVEP-based BCIs.
12 April 2016
The Multiscale Poincare Plots package contains MATLAB scripts used to visualize time series by plotting Poincare plots of the original signal course grained at multiple time scales. A detailed description of the algorithm can be found in Multiscale Poincare plots for visualizing the structure of heartbeat time series.
10 April 2016
The Logistic Regression HSMM based Heart Sound Segmentation package contains MATLAB code used to segment phonocardiogram (PCG) recordings, and detect the four states of the heart cycle. This state of the art segmentation code by Springer is used in the sample entry of the 2016 PhysioNet/CinC Challenge. A detailed description of this segmentation algorithm can be found in Logistic Regression-HSMM-based Heart Sound Segmentation.
31 March 2016
The Steady State Visually Evoked Potentials Database contains 16 channel EEG recordings of five subjects exposed to flashing LEDs at different frequencies. This dataset is used and described in A New Method of Spatial Filters Design for Brain-Computer Interface Based on Steady State Visually Evoked Potentials.
09 March 2016
The newly contributed software for Modeling of Heart Rate Variability Including the Effect of Sleep Stages implements a model for simulating healthy nighttime heart rate variability based on the properties of sleep observed in real data. Also included are 20 RR time series generated by the model. The model was first proposed in “Modeling heart rate variability including the effect of sleep stages,” by Soliński et al in CHAOS 26, 023101 (2016).
04 March 2016
We are pleased to announce the 2016 PhysioNet/Computing in Cardiology Challenge: Classification of Normal/Abnormal Heart Sound Recordings. For this year's Challenge, we have released a collection of 3,125 phonocardiograms from a variety of clinical and non-clinical sources. We invite participants to develop algorithms to determine, based on a short heart sound recording, whether the patient should be referred on for an expert diagnosis.
04 March 2016
The Transfer Entropy With Partitioning package is a repository of MATLAB functions that can estimate transfer entropy (information flow) from one time series to another using a non-parametric partitioning algorithm. Also included is an example data set that the implemented algorithms can be applied to. These algorithms are used and described in Transfer Entropy Estimation and Directional Coupling Change Detection in Biomedical Time Series.
04 March 2016
The MMG Database contains uterine magnetomyographic (MMG) signals recorded using the 151 channel SARA (SQUID Array for Reproductive Assessment) system installed at UAMS, Little Rock, USA. The dataset and its collection methods are described in Characterizing the Propagation of Uterine Electrophysiological Signals Recorded with a Multi-Sensor Abdominal Array in Term Pregnancies
18 February 2016
The Physiologic Response to Changes in Posture Database contains a collection of physiological recordings (ECG and ABP) from ten healthy subjects in response to a slow tilt, a fast tilt, and a standing-up maneuver. The dataset and its collection methods are described in Circulatory Response to Passive and Active Changes in Posture
18 December 2015
The Motion Artifact Contaminated ECG Database contains short duration ECG signals recorded from a single healthy 25-year-old male performing different physical activities to study the effect of motion artifacts on ECG signals and their sparsity. The dataset and its collection method are described in Rate-Adaptive Compressed-Sensing and Sparsity Variance of Biomedical Signals
25 November 2015
The kl-single-uncentralized subdirectory contains another new set of single lead KL basis functions for the ST segments, and their subsequent normalized and non-normalized KL coefficients. The set of clean heart beats from which the ST segments are extracted slightly differ from those of the previously derived 2011 KL dataset. More importantly, this time the KL coefficients are not centralized by their mean values.
9 November 2015
Data Chromatix is a technique for visualizing trends in biomedical signals by bringing memory of the system's past behavior into the current display window. This package was developed at the Wyss Institute at Harvard by A. Burykin, S. Mariani, T. Silva and T. Henriques, and is described in "Remembrance of time series past: simple chromatic method for visualizing trends in biomedical signals," Burykin A, Mariani S, Henriques T, Silva TF, Schnettler WT, Costa MD, Goldberger AL. Physiol Meas 2015;36(7):N95.
9 November 2015
ECG-kit This toolbox is a collection of MATLAB tools that Mariano Llamedo Soria used, adapted or developed during his PhD and post-doc work with the Besicos group at University of Zaragoza, Spain and at the National Technological University of Buenos Aires, Argentina. The main feature of this toolbox is that it allows the use of several popular algorithms for ECG processing, including: Algorithms from Physionet's WFDB software package; QRS detectors, such as gqrs, wqrs, wavedet, ecgpuwave, Pan & Tompkins, EP limited; Wavelet-based ECG delineator; Pulse wave detectors as wabp and wavePPG; and a2hbc and EP limited heartbeat classifiers.
19 May 2015
Smart Health for Assessing the Risk of Events via ECG (SHAREE database). The SHAREE database was developed in order to investigate the possibility of identifying hypertensive subjects at higher risk to develop vascular events based on Heart Rate Variability analysis. The database was created by Paolo Melillo, Raffaele Izzo, Ada Orrico, Paolo Scala, Marcella Attanasio, Marco Mirra, Nicola De Luca, and Leandro Pecchia as part of the “Smart Health and Artificial intelligence for Risk Estimation” (SHARE) project, which seeks ways to prevent cardiovascular events and falls in people over 65.
9 May 2015
Icelandic 16-electrode Electrohysterogram DataBase (EHGDB). A new dataset of 122 16-electrode EHG recordings performed on 45 pregnant Icelandic women has been published in PhysioBank. The data was contributed by Ásgeir Alexandersson, who performed the recordings at Akureyri Primary Health Care Centre, Akureyri Hospital and Landspitali University Hospital. A detailed description of the database has been published in Nature's new journal Scientific Data 2, Article number: 150017 (2015).
14 February 2015
The PhysioNet/Computing in Cardiology Challenge 2015 is now open. This year's challenge is 'Reducing False Arrhythmia Alarms in the ICU'. False alarms in the ICU can lead to a disruption of care, impacting both the patient and the clinical staff through noise disturbances, desensitization to warnings and slowing of response times, leading to decreased quality of care. To address this issue, competitors are challenged to devise a method of processing all the available data to reduce false alarms with minimal or no effect on true (vital) alarms.
31 January 2015
Two new software packages have been added to PhysioToolkit! The first package, D3Maps, is a tool for visualizing the behavior of complex systems by means of the dynamical density delay mapping technique. This package was developed at the Wyss Institute by A. Burykin, L. Citi, M.D. Costa and A.L. Goldberger. The second software package, Multiscale Multifractal Analysis, is a time series analysis method designed to describe scaling properties of fluctuations within a signal. The software package was contributed by Jan Gierałtowski from Warsaw University of Technology.
22 January 2015
PhysioNet is pleased to announce that we are now an officially recommended repository for the journal Scientific Data (SciData). SciData is an open-access, peer-reviewed publication from the Nature Publishing Group focusing on scientifically valuable research datasets. SciData's primary article-type, the Data Descriptor, is designed to make your data more discoverable, interpretable and reusable. Users who have contributed data to PhysioNet are now invited to submit their unpublished data as a Data Descriptor to Scientific Data! Pre-submission enquires are welcome at scientificdata@nature.com.
12 December 2014
NEW DATABASE ADDED: Combined measurement of ECG, Breathing, and Seismocardiograms Database (CEBSDB). A dataset of 60 records from 20 volunteers has been contributed to PhysioBank by Miguel Angel Garcia Gonzalez and Ariadna Argelagos Palou from the Universitat Politecnica de Catalunya. Each record contains two ECGs, a respiration, and a seismocardiogram signals. The database was designed to check if errors in RR series are influenced by breathing, and if there is a significant variability in RR series estimated from ECGs versus seismocardiograms.
3 November 2014
Two new software packages have been added to the PhysioTookit library. FECGSyn is a new Foetal ECG Waveform Generator contributed by Joachim Behar and colleagues in Gari Clifford's group at the University of Oxford. The second package, the Random Search Toolbox, is a MATLAB toolbox for selecting model hyper-parameters via random search, also contributed by Joachim Behar and colleagues in Gari Clifford's group.
4 April 2014
PhysioNet users with an interest in sleep physiology now have access to the web site of the National Sleep Research Resource (NSRR), which hosts large annotated collections of EDF polysomnograms and related clinical data elements from well-characterized research cohorts and clinical trials. The first data set available includes over 8,000 studies from exams 1 and 2 of the Sleep Heart Health Study, with scheduled new data releases every quarter from additional data sets. NSRR also provides open-source software for viewing and analyzing these data.
6 March 2014
The ECG-ID Database is a set of 310 ECGs from 90 volunteers, created and contributed to PhysioBank by Tatiana Lugovaya, who used the data in her master's thesis on the topic of biometric human identification using the ECG. An excellent summary of this thesis, with a discussion of the challenges in using ECGs as biometrics, and a comparison of the author's methods and results with those of three previous studies, is also available.
4 March 2014
A set of high-resolution multichannel EEG recordings — created and contributed by Luca Citi, Riccardo Poli, and Caterina Cinel — was generated as part of a study aimed at identifying the factors limiting the performance of brain-computer interfaces (BCIs) based on event-related potentials (ERPs), in order to improve the transfer rate and the usability of these interfaces. Twenty recordings of each of 10 participants include annotated 64-channel EEGs and 4-channel EOGs, generated while the participants focused on specified target characters displayed by a traditional matrix speller.
3 March 2014
A collection of motion artifact contaminated fNIRS and EEG data has been contributed to PhysioBank by Kevin Sweeney and colleagues at the National University of Ireland in Maynooth. The data set contains examples of functional near-infrared spectroscopy (fNIRS) and electroencephalogram (EEG) recordings that have been created for evaluating artifact removal methods. In each such recording, one or two pairs of similar physiological signals have been acquired from transducers in close proximity. One signal of each pair is contaminated by motion artifact, documented in each case by simultaneously recorded outputs of 3-axis accelerometers affixed to each transducer.
18 February 2014
The CTU-UHB Intrapartum Cardiotocography Database, from the Czech Technical University (CTU) in Prague and the University Hospital in Brno (UHB), contains 552 cardiotocography (CTG) recordings, which were carefully selected from 9164 recordings collected between 2010 and 2012 at UHB. The CTG recordings start no more than 90 minutes before actual delivery, and each is at most 90 minutes long. Each CTG contains a fetal heart rate (FHR) time series and a uterine contraction (UC) signal, each sampled at 4 Hz. Each CTG is accompanied by maternal, delivery, and fetal clinical details.
30 January 2014
A contribution of simulated fetal phonocardiograms is now available in PhysioBank. The synthetic PCGs exhibit a realistic range of signal-to-noise ratios, with simulated maternal heart and organ sounds, fetal movements, and environmental sounds.
7 January 2014
The 15th annual PhysioNet/CinC Challenge, Robust Detection of Heart Beats in Multimodal Data, is now underway. Read the first announcement, and study the training data set and a sample entry.

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Updated Thursday, 15 September 2016 at 22:30 SGT

PhysioNet is supported by the National Institute of General Medical Sciences (NIGMS) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under NIH grant number 2R01GM104987-09.